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Rheology Testing Services

Supporting R&D to Manufacturing. Applying the appropriate science, to answer the questions, to drive the projects to meet the business needs.

Meeting the Need

Since 2017 RTS has provided flexible rheological assay options and parameters with rapid turnaround including a detailed report and follow-ups to ensure client satisfaction as outlined in the "Applications, Assays & Deliverables" tab above.  In addition to the assays listed in the "Basic Assays" tab above, many "1-off" options not listed are often performed to ensure tailored solutions for your specific needs.

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Viscosity

Viscosity can be determined by several approaches across a wide range of conditions.  These may include assaying across an increasing, followed by decreasing shear rate (or shear stress) with either a continuous non-equilibrium ramp or with discrete steps that allow the sample to stabilize at each increment.

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Yield Stress

This assay is used to screen and model numerous properties and processes such as mass transfer through pipes for manufacturing (Poiseuille's Law), pumpability, sedimentation potential (Stokes' Law), ease of product delivery (syringability, injectability, spreadability) and sensory.

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Thixotropy

Thixotropy investigations are very helpful to provide insight into the effects of product manufacturing processes, handling, and dispensing.

Rheometer vs Viscometer

A rheometer provides much more insight into your product properties. A viscometer is well suited as a QC tool - simple to use and relatively inexpensive to purchase, maintain and operate.

About Rheology Testing Services

Knowing your sample viscosity may be important; however, understanding its more detailed rheological profile and potential implications may be highly value added and critical.

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Rheology Testing Services (RTS) offers an array of analyses to support early R&D through manufacturing across many materials and industries.  These assays efficiently and precisely probe material response to various forces and conditions to model processes and applications to which your material may be exposed.  Material that is exposed to force, however minimal - even gravity, may reversibly or even irreversibly change from the effects of stress, shear, strain and temperature.  Output from these assays, described in more detail in the above tabs may provide better understanding of your materials to support R&D, process optimization, manufacturing, packaging, performance, efficacy, and tactile properties.  Other applications include regulatory considerations to demonstrate or disprove structural equivalence (Q3, ref 1-3), in-process control, batch consistency and stability.

 

1. "Draft Guideline on Quality and Equivalence of Topical Products" European Medicines Agency (18Oct2018) 

      (https://www.ema.europa.eu/en/quality-equivalence-topical-products#current-version-section)

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2. "Generic Development of Topical Dermatologic Products: Formulation Development, Process Development, and Testing of Topical Dermatological Products"        AAPS J. 2013 Jan; 15(1): 41-52 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535108/)

 

3.  "Testing Topicals: Analytical Strategies for the In-Vitro Demonstration of Bioequivalence" Pharm Tech Sept 2018  

      (http://www.pharmtech.com/testing-topicals-analytical-strategies-vitro-demonstration-bioequivalence? pageID=1)

Here to Help
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Do you need rheology support?

Need rheology support but not sure which assays and parameters are appropriate?
No problem! You've come to the right place!
 
RTS will closely partner with you to efficiently and effectively address your technical needs with flexibility and minimal bureaucracy.  

“We contacted Mark to outsource our rheology characterization tests. Not only did he provide the required results in a timely manner, he went above and beyond to provide detailed reports with the right context to help us understand the results, especially when the data showed unexpected results. He is always available to discuss the results in more detail as needed. His expertise in non-Newtonian fluids helped us successfully complete our project.”  

 

- Siddharth Talapatra, PhD  Group Lead, Research   Heat Transfer Research, Inc.

TESTIMONIALS

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